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Pituitary macroadenoma: analysis of intercarotid artery distance compared to controls

Macroadenoma de hipófise: análise da distância intercarotídea comparada a controles

ABSTRACT

Objective

To evaluate the intercarotid distance (ICD) of patients with pituitary macroadenoma and compare to heatlhy controls.

Method

We retrospectively reviewed contrast-enhanced MRI images from twenty consecutive patients diagnosed with non-functioning pituitary macroadenoma, measured the ICD at two different levels (petrous segment – ICD1 and horizontal cavernous segment – ICD2) and compared to twenty paired controls.

Results

There was no statistically significant difference of the mean ICD1 between the groups and subgroups. For the ICD2 there was statistically significant difference between the case and controls. However, there was no significant difference between the patients with smaller adenomas and the controls. In contrast, the patients with giant adenomas showed statistically significantly higher ICD2 than the controls.

Conclusion

The ICD at the horizontal segment of the cavernous carotid tends to be wider in patients with giant pituitary adenomas than in healthy individuals or patients with smaller adenomas.

Pituitary gland; pituitary disease; internal carotid artery; endoscopy; sella turcica

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