This is a retrospective report of the frequency of severe hypoglycemia and the association between common mental disorders and type 1 diabetes mellitus treated with insulin analogues. Patients with severe hypoglycemia compared with those without this complication had a higher prevalence of positive screening for common mental disorders (88% vs.77%, respectively, p = 0.03).
Keywords
Severe hypoglycemia; type 1 diabetes; common mental disorders
| Characteristic | Overall study population (N = 516) |
Severe hypoglycemia | p | |
|---|---|---|---|---|
| No (N = 409) |
Yes (N = 101) |
|||
| Age (years) | 35 (28-45) | 34 (27-45) | 38 (31-49) | 0.016 |
| Sex (% women) | 259 (52) | 199 (50) | 59 (56) | 0.446 |
| Ethnicity (% white) | 446 (88) | 348 (87) | 91 (90) | 0.552 |
| School (% complete higher education) | 189 (37) | 162 (40) | 27 (26) | 0.006 |
| Age at diagnosis (years) | 17 (11-27) | 17 (11-27) | 18 (11-28) | 0.664 |
| Diabetes duration (years) | 18 (11-25) | 17 (10-24) | 19 (13-27) | 0.012 |
| Duration of use of insulin analogues (years) | 5 (3-10) | 5 (3-10) | 5 (2-10) | 0.917 |
| Body mass index (kg/m2) | 24 (22-27) | 24 (22-27) | 25 (22-27) | 0.688 |
| Beta-blocker use | 27 (5) | 16(4) | 11(10) | 0.023 |
| Rapid-acting insulin analogue use | 458 (91) | 360 (88) | 94 (93) | 0.439 |
| Long-acting insulin analogue use | 431 (86) | 340 (83) | 85 (84) | 0.539 |
| GHQ-12, CMD screening (≥3) | 395 (77) | 301 (77) | 90 (88) | 0.027 |
| DTSQs total score | 32 (29-35) | 32 (29-35) | 31 (27-34) | 0.007 |
