PURPOSE:
To assess the systemic response of pigs to the intraperitoneal implantation of polypropylene mesh associated with chitosan-based film with a degree of deacetylation of 95%.
METHODS:
Blood samples were collected 24 hours before, and two and seven days after surgery. Systemic reactions were evaluated based on white blood cell count, C-reactive protein, and total serum protein, albumin and globulin levels.
RESULTS:
The systemic response was proportional to the composite response induced by polypropylene mesh, and the tissue inflammatory response was higher in the PP group (p=0.0033).
CONCLUSION:
The polypropylene mesh/chitosan-based film composite did not elicit a systemic response in pigs.
Chitosan; Peritoneum; Surgical Mesh; Swine
