Experimental model of double wounds on the rats back , in order to study the skin cicatrization process on rat treated with cellulose coat

Modelo experimental de dupla lesão no dorso de ratos, para estudo do processo de cicatrização da pele, utilizando-se a película de celulose

To the present study were used males rats (Rattus Norvegicus, var. Albinus, Rodentia Mammalia) EPM-1 Wistar, which came from Biotério Central da UNIFESP-EPM. Each animal was submitted to two wound of circular shape, made with a "punch", with superficial cuts of 2 cm diameter; located on medium line of dorsal region. In the present study, one wound was re-covered with the cellulose coat and the other serves as a control. This experimental form, makes it possible to us realize different studies such as macroscopic aspects of the wounds as well morphometric and morphological parameters analysis.

Wound cicatrization; Biological coat; Cellulose coat; Burns