Action of AlGaInP laser and high frequency generator in cutaneous wound healing. A comparative study¹

ABSTRACT

PURPOSE:

To evaluate in a macroscopic, histological and histomorphometric manner the healing process of cutaneous wounds in mice.

METHODS:

The sample consisted of 40 male mice and was divided in four groups: 1^st group (control, n=10), 2^nd group (High Frequency Generator - HF, the maximum amplitude range, 120s, n=10), 3^rd group (AlGaInP Laser 660 nm, 30mW power, 5 J/cm², applying scan mode, 120s, n=10) and 4^thgroup (AlGaInP Laser 660 nm, 30 mW power, 8 J/cm², applying scan mode, n=10). The surgical incision was made with an 8 mm diameter punch perpendicularly to the back of the animal. The statistical analysis was achieved by the statistical test One Way Anova post hoc Tukey Test and significance at p<0.05 in GraphPad Prism program.

RESULTS:

It was observed that in the acute phase the AlGaInP Laser at 5 J/cm² provided a greater stimulus to healing, and both lasers were effective in the remodeling phase.

CONCLUSION:

The AlGaInP lasers from 5 J/cm² to 8 J/cm² showed better biomodulatory results in the acute and remodeling phases respectively, however, the HF was less effective than the laser, providing significant benefits only in the acute phase of tissue repair.

Key words:
Wound Healing; Skin; Lasers, Gas; Ozone; Mice