Ocular manifestation of vertical transmission of dengue: case report

Manifestação ocular de transmissão vertical de dengue: relato de caso

ABSTRACT

A 7-week-old male delivered by cesarean section presented with a positive serology for dengue along with preretinal and retinal hemorrhages, vitreous opacities and cotton wool spots. The patient and his mother had positive serologies for Non Structural Protein 1 (NS1) by ELISA. Retinal and vitreous findings improved over a sixteen-week period. Spectral domain optical coherence tomography (OCT) showed preserved macular architecture. In this case report, we suggest that retinal and vitreous changes may be the ocular presenting features of vertically transmitted dengue in newborns, and that those findings may resolve with no major structural sequelae.

Keywords:
Dengue; Pregnancy complication, infectious; Infectious disease transmission, vertical; Eye manifestations; Retinal hemorrhage; Vitreous hemorrhage; Human; Infant, newborn, diseases; Case reports