The aim of this study was to evaluate the immune response of maned wolves vaccinated with modified-live vaccine (MLV) against canine distemper virus (CDV) and canine parvovirus (CPV), developed for use in domestic dogs. Serum samples were collected from 47 maned wolves from zoos and were analysed by the serum neutralization (SN) and hemagglutination-inhibition (H) tests against CDV and CPV, respectively, being 361 samples tested for CDV and 353 for CPV. The results showed that 72% of samples had SN titers > or = 100 against CDV and 98% developed H titers > or = 80 against CPV. Maned wolves without vaccination history were able to develop antibodies to CDV and CPV after the vaccination. Specimens with vaccination history that showed titers considered protective mantained their response over the period of one year after the vaccination. The MLV used in this study proved to be safe and immunogenic to adult and pup maned wolves.
Maned wolf; vaccination; canine distemper; canine parvovirus