Resumo Pretende-se, no presente artigo, demonstrar que, nos livros para crianças, a relação dialogal e a fusão intersemiótica entre as linguagens verbal e icónica potenciam a instauração de uma atmosfera poética imprescindível na formação estético-literária da criança pré-leitora, que, no processo hermenêutico de apropriação e construção de sentidos, sozinha ou pela mão do adulto-mediador, se assume como um ser cognoscente e cocriador do universo textual, encetando um percurso enunciativo de intensa cooperação interpretativa. Pretende-se igualmente problematizar o lugar dos livros no jardim de infância e o seu contributo para o desenvolvimento cognitivo, social e emocional da criança em idade pré-escolar, atribuindo pedagogicamente ao adulto-mediador um papel determinante nesse processo de construção do ser em crescimento nomeadamente através do recurso ao livro de qualidade estética e literária.

Abstract It is intended in this article to demonstrate that in children's books, the dialogical relationship and intersemiotic fusion between verbal and iconic languages create a poetic atmosphere of real meaning that seems indispensable in aesthetic-literary formation of the pre-reading child. In fact, in the hermeneutical process of appropriation and construction of meanings, alone or by the hand of an adult-mediator, the child is a co-creator of the textual universe, engaging an enunciative journey of intense interpretative cooperation. It is also intended in this article to question the place of books in the kindergaten and their contribution to the cognitive, social and emotional development of children in preschool age, giving to the adult-mediator a decisive role in this construction process particularly through the use books of aesthetic and literary quality.

Objetivo: evaluar la disfunción endotelial a través de la vasodilatación mediada por flujo (VMF) en la arteria braquial en pacientes fumadores con periodontitis crónica avanzada y compararla con pacientes fumadores sin enfermedad periodontal, para determinar si hay diferencias en cuando a disfunción endotelial entre quienes presentan o no periodontitis crónica avanzada. Métodos: se incluyeron 30 pacientes con hábito de tabaquismo, 15 con periodontitis crónica avanzada y 15 sin periodontitis. Se realizó historia clínica completa, exámenes de laboratorio y prueba de vasodilatación mediada por flujo de la arteria braquial. Resultados: el estudio mostró que había diferencias significativas en los diámetros finales, resultantes de vasodilatación mediada por flujo (p=0,0328), con menores valores finales para quienes tenían enfermedad periodontal. Las diferencias en las respuestas porcentuales y en el número de personas con disfunción determinada dicotómicamente, no alcanzaron significación estadística. Conclusión: se observó que el grupo de pacientes con periodontitis crónica avanzada tuvo diámetros resultantes luego de la prueba que fueron significativamente menores que los del grupo de controles. Aunque al evaluar las diferencias en porcentajes no se alcanzó significación estadística, el estudio mostró una respuesta claramente menor en vasodilatación en el grupo con enfermedad periodontal.

Objective: To evaluate endothelial dysfunction through flow-mediated vasodilation (FMD) in the brachial artery in smokers with advanced chronic periodontitis and compare it with smokers without periodontal disease, to determine whether there are differences in endothelial dysfunction among those with or without advanced chronic periodontitis. Methods: We included 30 patients with smoking habit, 15 with advanced chronic periodontitis and 15 without periodontal disease. We performed a complete medical history, laboratory tests and flow-mediated vasodilation test of the brachial artery. Results: The study showed that there were significant differences in the final diameters, resulting from flow-mediated dilation (p = 0.0328), with lower final values for those with periodontal disease. The differences in the percentage responses and the number of people with specific dysfunction determined dichotomously did not reach statistical significance. Conclusion: We observed that the group of patients with advanced chronic periodontitis had after the test resulting diameters that were significantly lower than those in the control group. Although when evaluating differences in percentages no statistical significance was found, the study showed a clearly lower response in vasodilation in the group with periodontal disease.