ABSTRACT The article presents the results of a research process focused on the digitization and public availability of the ¡Adelante! The newspaper of the Usina Popular de Tandil, a press organ published in the town of Tandil, Argentina, between 1934 and 1942. This publication was born in the process of creating the Popular Power Plant, an entity that sought to provide accesibility and quality service to bring electrical energy to the people of Tandil. The digitization of these archive materials and their availability in open access repositories raises, on the one hand, a series of questions about the relationships established between communication processes, digital technologies and the public policies that seek to carry it out, whereas at the same time, it demanded the formation of a multidisciplinary team that involved dialogue with historical research that contributes to the construction of a history of the press in medium-sized cities in the province of Buenos Aires.

RESUMEN El artículo presenta los resultados de un proceso de investigación centrado en la digitalización y puesta en disponibilidad pública del archivo de ¡Adelante! El Periódico de la Usina Popular de Tandil, un órgano de prensa editado en la localidad bonaerense de Tandil, Argentina, entre 1934 y 1942. Dicha publicación nace en el proceso de creación de la Usina Popular, una entidad que buscó brindar un servicio accesible y de calidad para llevar energía eléctrica a los tandilenses. La digitalización de estos materiales de archivo y su puesta a disposición en repositorios de acceso abierto plantea, por un lado, una serie de interrogantes acerca de las relaciones que se establecen entre los procesos comunicacionales, las tecnologías digitales y las políticas públicas que pugnan llevarla adelante, al mismo tiempo que exigió la conformación de un equipo multidisciplinario que involucró el diálogo con las investigaciones históricas que contribuyen a la construcción de una historia de los medios de prensa de ciudades medias de la provincia de Buenos Aires.

RESUMO O artigo apresenta os resultados de um processo de pesquisa focado na digitalização e disponibilização pública do arquivo de ¡Adelante! El Periódico de la Usina Popular de Tandil, órgão de imprensa publicado na cidade de Tandil, em Buenos Aires, Argentina, entre 1934 e 1942. Esta publicação nasceu no processo de criação da Usina Popular, entidade que buscava fornecer um serviço acessível e de qualidade para levar energia elétrica à população de Tandil. A digitalização destes materiais arquivísticos e a sua disponibilização em repositórios de acesso aberto levanta, por um lado, uma série de questões sobre as relações estabelecidas entre os processos de comunicação, as tecnologias digitais e as políticas públicas que procuram realizá-lo, que exigiu a formação de uma equipe multidisciplinar que envolveu o diálogo com as pesquisas históricas que contribuem para a construção de uma história da mídia impressa nas cidades médias da província de Buenos Aires.

Abstract In Brazil, 65% of the electric power production comes from hydroelectric power plants (HPPs). In some cases, these power plants divert the course of rivers, resulting in regions impacted by the absence of water, which are known as reduced fow sections (RFS). These sections are regulated by legislation and aim to maintain the minimum fow necessary to preserve the fauna, flora, fish, and human consumption in the region. Depending on the time of year, this minimum flow, also known as ecological flow (residual flow), can reach significant values, resulting in the interruption of power generation in these HPPs. This article presents a study case of two hydroelectric power plants located in different Brazilian states. The objective of this study is to explore the feasibility of implementing auxiliary generator groups that can operate uninterruptedly at different drop heights while ensuring the preservation of residual flow during low flow periods or taking advantage of the overflow flow by spillways during high flow periods. This auxiliary system would use the same set of structures and transmission systems as the main power plant, minimizing environmental impacts and implementation costs, allowing this solution to be implemented in HPPs that face this type of problem in Brazil. The results obtained indicate that HPPs with larger reservoirs have a greater ability to maintain residual flows with minimal generation loss and that run-of-the-river power plants are the most impacted by the maintenance of residual flow.

Abstract Cornstarch is one of the most used depressants in mineral flotation operations. However, corn is a costly input for the Brazilian mineral industry, since its main destination is to serve the animal and human food market and exports. In this study, sorghum and millet, two cheaper starch sources, were tested in order to reduce the mining dependence on corn. A simplex lattice design mixture {3,4} was used to evaluate the best proportion of corn, millet, and sorghum flours to be used as a pyrochlore depressant in relation to the industrially adopted cornstarch (Stargill 6172 supplied by Cargill). Flotation tests were carried out on a bench scale Denver flotation cell. All tests were performed in triplicate in a single rougher stage. The results found suggest that sorghum flour was a stronger pyrochlore depressant compared to corn and millet flours, with an average Nb2O5 content of 1.72 ± 0.05% and recovery of 80.75 ± 4.10%. These values were close to the ones found with Stargill 6172 (1.32 ± 0.02 and 80.95 ± 1.13%, Nb2O5 content and recovery, respectively), the industrially adopted depressant. The marked price and the easiness in the production of the flour in relation to the extraction of starches makes the sorghum flour a potential pyrochlore depressant, replacing the industrially used cornstarch.

In light of the need for social isolation caused by the pandemic, in-person classes were suspended, making way for emergency remote teaching (ERT). This abrupt transition allowed for no planning or preparation for the individuals involved in the teaching-learning process. In this context, it fell upon the educators to adapt to this new, atypical reality. The aim of this study was to describe the characteristics and challenges faced by teachers at IF Sudeste MG - Campus Rio Pomba during ERT and its impacts on the teaching-learning process. To achieve this, a structured questionnaire with the participation of 41 educators was used. Difficulties related to pedagogical training, use of technological tools and active teaching methodologies (ATM), and the adaptive process of educators were highlighted. Educators did not consider ERT capable of efficiently fulfilling the objectives of the disciplines, although they acknowledged the necessary institutional support. The self-assessment of teaching performance during ERT was predominantly positive. Prior to ERT, the use of ATM was lower, especially among educators above 40 years old and males; furthermore, difficulties in using ATM increased with age, with more males reporting not using them. The adaptation to ERT was considered moderate, and more educators aged 40 to 49 reported dissatisfaction with the work environment. Educators above 40 years old and females had a higher incidence of negative psychological symptoms during ERT. This study highlights the challenges educators faced during ERT, especially those over 40 years old and females.

Ante la necesidad de aislamiento social causada por la pandemia, las clases presenciales fueron suspendidas dando paso a la enseñanza remota de emergencia (ERE). Esta transición abrupta no permitió ningún tipo de planificación o preparación para los actores involucrados en el proceso de enseñanza-aprendizaje. En este contexto, a los docentes les correspondió el desafío de adaptarse a esta nueva realidad atípica. El objetivo de este estudio fue describir las características y desafíos enfrentados por los profesores del IF Sudeste MG - Campus Rio Pomba durante la ERE y sus impactos en el proceso de enseñanza-aprendizaje. Se aplicó un cuestionario estructurado con la participación de 41 docentes. Se evidenciaron dificultades relacionadas con la formación pedagógica, el uso de herramientas tecnológicas y de metodologías activas de enseñanza (MAE). Los docentes no consideraron que la ERE fuera capaz de cumplir eficientemente con los objetivos de las disciplinas, a pesar de reconocer el apoyo institucional necesario. La autoevaluación del desempeño docente durante la ERE fue predominantemente positiva. Antes de la ERE, el uso de MAE era menor, especialmente entre los docentes mayores de 40 años y los hombres; además, las dificultades en el uso de MAE aumentaron con la edad, siendo que más hombres informaron no utilizarlas. La adaptación a la ERE fue considerada moderada, y más docentes de 40 a 49 años informaron insatisfacción con el ambiente de trabajo. Los docentes mayores de 40 años y las mujeres tuvieron una incidencia de síntomas psicológicos negativos durante la ERE y enfrentaron mayores desafíos.

Diante da necessidade do isolamento social causada pela pandemia, as aulas presenciais foram suspensas dando lugar ao ensino remoto emergencial (ERE). Essa migração abrupta não permitiu nenhum planejamento ou preparação dos atores envolvidos no processo de ensino-aprendizagem. Nesse contexto, coube ao docente o desafio de adaptar-se a essa nova realidade atípica. Dessa forma, objetivou-se com o presente estudo, descrever as características e desafios enfrentados pelos professores do IF Sudeste MG - Campus Rio Pomba durante o ERE e seus impactos no processo de ensino-aprendizagem. Para isso, foi utilizado um questionário estruturado com participação de 41 docentes. Dificuldades relacionadas a formação pedagógica, uso de ferramentas tecnológicas e de metodologias ativas de ensino (MAE) e processo adaptativo dos docentes foram evidenciadas. Docentes não consideraram o ERE capaz de suprir eficientemente os objetivos das disciplinas, apesar de considerarem que houve apoio institucional necessário. A autoavaliação do desempenho docente durante o ERE foi predominantemente positiva. Antes do ERE, o uso de MAE era menor, especialmente entre os docentes acima de 40 anos e homens, além disso, as dificuldades do uso de MAE aumentaram com a idade, sendo que mais homens relataram não as utilizar. A adaptação ao ERE foi considerada mediana e, mais docentes de 40 a 49 anos relataram insatisfação com o ambiente de trabalho. Docentes acima de 40 anos e mulheres tiveram maior incidência de sintomas psicológicos negativos no ERE. Esse trabalho evidencia o desafio que os docentes passaram durante o ERE, especialmente para aqueles maiores de 40 anos e mulheres.

This work addresses affectivity as one of the components of teaching-learning relationships in Early Childhood Education. More specifically, it discusses the repercussions of different social markers (gender, race/color, and the presence of disabilities or neurodevelopmental disorders) on expressions of affection towards children in the initial stage of basic education. Drawing on the theoretical contributions of Henri Wallon regarding affectivity as a form of interaction with the environment, as well as social childhood studies, the aim was to ascertain whether certain children, based on their characteristics, were more likely to be the target of affectionate demonstrations by teachers and other adults present in the classroom, while others, also due to their specificities, tended to be treated with indifference and lack of affection. An ethnographic type of observation was conducted in Early Childhood Education institutions in a municipality in the metropolitan region of Belo Horizonte (Minas Gerais/Brazil). An association was identified between the children's profiles and the greater or lesser presence of verbal and non-verbal expressions of affection, as well as the persistence of different forms of discrimination and physical and symbolic violence towards the children.

Este trabajo aborda la afectividad como uno de los componentes de las relaciones de enseñanza-aprendizaje en la Educación Infantil. Más específicamente, analiza las repercusiones de diferentes marcadores sociales (género, raza/color y la presencia de discapacidades o trastornos del neurodesarrollo) en las expresiones de afecto hacia los niños en la etapa inicial de la educación básica. Basándose en las contribuciones teóricas de Henri Wallon en lo que respecta a la afectividad como una forma de interacción con el entorno, así como en los estudios sobre la infancia en la sociedad, el objetivo fue determinar si ciertos niños, en función de sus características, eran más propensos a ser el blanco de demostraciones afectuosas por parte de los maestros y otros adultos presentes en el aula, mientras que otros, también debido a sus especificidades, tendían a ser tratados con indiferencia y falta de afecto. Se realizó un tipo de observación etnográfica en instituciones de Educación Infantil en un municipio de la región metropolitana de Belo Horizonte (Minas Gerais/Brasil). Se identificó una asociación entre los perfiles de los niños y la mayor o menor presencia de expresiones verbales y no verbales de afecto, así como la persistencia de diferentes formas de discriminación y violencia física y simbólica hacia los niños.

Este trabalho aborda a afetividade como um dos componentes das relações de ensino-aprendizagem na Educação Infantil. Mais especificamente, discute as repercussões de diferentes marcadores sociais (gênero, raça/cor e presença de deficiência ou transtorno do neurodesenvolvimento) nas manifestações de afeto para com as crianças da primeira etapa da educação básica. Tendo como base as contribuições teóricas de Henri Wallon sobre a afetividade como forma de interação com o meio; e os estudos sociais da infância, buscou-se verificar se algumas crianças, por suas características, seriam mais propensas a serem alvo de demonstrações afetivas por parte de professores e demais adultos presentes em sala; enquanto outras – também por suas especificidades – tenderiam a serem tratadas com indiferença e desafeição. Foi desenvolvida observação de tipo etnográfica em instituições de Educação Infantil de um município da região metropolitana de Belo Horizonte (Minas Gerais/Brasil). Identificou-se associação entre o perfil das crianças e a maior ou menor presença de manifestações verbais e não verbais de afeto, bem como a persistência de diferentes discriminações e violências físicas e simbólicas para com as crianças.

Abstract Background: Only a fraction of patients with cutaneous lupus erythematosus (CLE) will eventually progress toward systemic disease (SLE). Objective: To find inflammatory biomarkers which could predict the progression of cutaneous lupus erythematosus (CLE) into systemic lupus erythematosus (SLE) using immunohistochemical (IHC) assays. Methods: Immunohistochemical markers for cytotoxic, inflammatory, and anti-inflammatory responses and morphometric methods were applied to routine paraffin sections of skin biopsies, taken from lesions of 59 patients with discoid lupus, subacute lupus, and lupus tumidus. For the diagnosis of SLE, patients were classified by both the American College of Rheumatology (ACR-82) and the Systemic Lupus International Collaborating Clinics (SLICC-12) systems. Results: Skin samples from CLE/SLE +patients presented higher expression of IL-1β (ARC-82: p = 0.024; SLICC-12: p = 0.0143) and a significantly higher number of cells marked with granzyme B and perforin (ARC: p = 0.0097; SLICC-12: p = 0.0148). Biopsies from CLE/SLE- individuals had higher expression of IL-17 (ARC-82: p = 0.0003; SLICC-12: p = 0.0351) and presented a positive correlation between the density of granzyme A+and FoxP3+ cells (ARC-82: p = 0.0257; SLICC-12: p = 0.0285) and CD8+ cells (ARC-82: p = 0.0075; SLICC-12: p = 0.0102), as well as between granulysin-positive and CD8+ cells (ARC-82: p = 0.0024; SLICC-12: p = 0.0116). Study limitations: Patients were evaluated at a specific point in their evolution and according to the presence or not of systemic disease. The authors cannot predict how many more, from each group, would have evolved towards SLE in the following years. Conclusions: In this cohort, immunohistochemical findings suggested that patients with a tendency to systemic disease will show strong reactivity for IL-1β, while those with purely cutaneous involvement will tend to express IL-17 more intensely.

Abstract Background: Methotrexate (MTX) is an alternative treatment for patients with moderate/severe atopic dermatitis (AD). Objective: The authors evaluated the effect of MTX on the cutaneous expression of cytokines and chemokines that are involved in the inflammatory response in adult AD patients who received treatment with methotrexate for 24 weeks. Methods: The authors conducted a prospective single-institution cohort study with 12 adults with moderate/severe AD who received oral MTX (15 mg/wk for 24 wks) and 10 non-atopic matched controls. The comparison was made of skin biopsies of lesional and non-lesional skin, pre- and post MTX treatment. The authors analyzed mean epidermal thickness and expression of IL-31, IL-31RA, OSMR, TSLP, Ki67, IL-4 mRNA, IL-6, IL-10, TNF-α, IFN-γ, TARC, and CCL-22. Results: There was a reduction in mean epidermal thickness (p = 0.021), an increase in IL-31RA expression (immunohistochemistry) in the epidermis (p = 0.016) and a decrease in IL-31 gene expression (p = 0.019) on lesional AD skin post-MTX treatment. No significant changes in the cutaneous expression of the other evaluated markers were identified. Study limitations: Small sample size and limited length of follow-up. Conclusions: Treatment with MTX in adults with moderate/severe AD reduced epidermal hyperplasia and changed the cutaneous expression of inflammatory cytokines and receptors that are mainly related to pruritus, including IL-31 and IL-31RA.

Abstract: The proper choice of raw materials and manufacturing parameters for Cross Laminated Timber is essential to promote the proper bonding of the lamellas, aiming at their application in construction. However, few Brazilian species are currently used in the production of Cross Laminated Timber. The aim of this work was to characterize the bonding quality of four Brazilian reforestation species (Pinus elliottii (pino ellioti), Eucalyptus grandis (eucalipto), Toona ciliata (toona) and Acrocarpus fraxinifolius (lazcar)) in the manufacture of Cross Laminated Timber with two-component polyurethane adhesive and five different pressure levels (from 0,1 MPa to 1,3 MPa). Bonding quality was evaluated through delamination and glue line shear tests based on the European standard. Delamination was affected by the wood species, and the best adhesion occurred for the Cross Laminated Timber manufactured with Pinus elliottii (pino ellioti) and Acrocarpus fraxinifolius (lazcar) at the bonding pressure of 0,7 MPa. Cross Laminated Timber bonding pressure did not affect the percentage of wood in the shear test fractured surface, whereas higher density Cross Laminated Timber showed higher percentages.

Resumo Objetivou-se realizar uma análise espacial da taxa de mortalidade hospitalar (TMH) por síndrome respiratória aguda grave (SRAG) atribuída à COVID-19 em crianças e adolescentes no Brasil no período de 2020 a 2021. Utilizou-se o método de cluster para agrupar as unidades federativas (UFs) com base na TMH. Em 2020, clusters com altas TMHs foram formados por UFs Norte/Nordeste. Em 2021, houve redução na TMH. Os clusters com maiores taxas permaneceram na região N/NE. Diferenças regionais foram observadas nas TMHs. Os achados podem refletir as desigualdades sociais e o acesso à atenção hospitalar, principalmente na faixa etária de menores de 1 ano pela gravidade da doença neste grupo.

Abstract The objective was to perform a spatial analysis of the hospital mortality rate (HMR) due to severe acute respiratory syndrome (SARS) attributed to COVID-19 among children and adolescents in Brazil from 2020 to 2021. A cluster method was used to group federal units (FUs) based on HMR. In 2020, clusters with high HMRs were formed by north/northeast FUs. In 2021, there was a reduction in HMR. Clusters with higher rates remained in the N/NE region. Regional differences were observed in the HMR. The findings may reflect social inequalities and access to hospital care, especially in the under 1-year-old age group due to the severity of the disease in this group.

Abstract The objective was to perform a spatial analysis of the hospital mortality rate (HMR) due to severe acute respiratory syndrome (SARS) attributed to COVID-19 among children and adolescents in Brazil from 2020 to 2021. A cluster method was used to group federal units (FUs) based on HMR. In 2020, clusters with high HMRs were formed by north/northeast FUs. In 2021, there was a reduction in HMR. Clusters with higher rates remained in the N/NE region. Regional differences were observed in the HMR. The findings may reflect social inequalities and access to hospital care, especially in the under 1-year-old age group due to the severity of the disease in this group.

Resumo Objetivou-se realizar uma análise espacial da taxa de mortalidade hospitalar (TMH) por síndrome respiratória aguda grave (SRAG) atribuída à COVID-19 em crianças e adolescentes no Brasil no período de 2020 a 2021. Utilizou-se o método de cluster para agrupar as unidades federativas (UFs) com base na TMH. Em 2020, clusters com altas TMHs foram formados por UFs Norte/Nordeste. Em 2021, houve redução na TMH. Os clusters com maiores taxas permaneceram na região N/NE. Diferenças regionais foram observadas nas TMHs. Os achados podem refletir as desigualdades sociais e o acesso à atenção hospitalar, principalmente na faixa etária de menores de 1 ano pela gravidade da doença neste grupo.

Abstract Background: The relationship between viral infections and host factors holds high hopes for identifying the role of Interferon Lambda 3 (IFNL3) and Interleukin 6 (IL-6) polymorphisms in the development of Chronic Liver Disease (CLD) in patients infected with hepatitis Delta virus (HDV) in the Western Brazilian Amazon. Methods: Cross-sectional study conducted with a cohort of 40 chronic HDV patients, 27 with CLD and 13 without evident liver damage. Biological samples from the participants were analyzed using the polymerase chain reaction (PCR) technique, followed by sequencing by the automated Sanger method. Results: The rs8099917 T allele, from the IFNL3 gene, showed a higher frequency in both groups; however, it was not possible to establish an association with HDV infection [OR = 1.42 (0.42 - 4.75; p = 0.556 (95% CI). For IL-6, the rs1800795 G allele was superior to rs1800795 C. Analyzing both distributions in the studied groups, any association with HDV was absent (p > 0.05). Conclusion: The results suggest that the rs8099917 T/G (IFNL3) and rs1800795 G/C (IL-6) polymorphisms are not associated with the evolution of HDV in the studied population.

Abstract The aim of this study was to assess temporal trends in the quality of health care during the first-week child check-up in primary care services stratified by municipal, health team and maternal characteristics. We conducted a cross-sectional study using data from the three cycles of the National Program for the Improvement of Access and Quality (PMAQ) (2012, 2014 and 2018). Adult service users with children aged up to 2 were interviewed. The outcome was “good quality health care in the first week of life”. Descriptive and time trend analyses were performed using variance-weighted least squares regression. The frequency of good quality care during the first-week check-up was 47.9% (95%CI 46.6-49.3) in 2012, 52.5% (95%CI 51.3-53.7) in 2014 and 53.3% (95%CI 52.2-54.4) in 2018, with an annual increase of 0.73 pp (p<0.001). The annual increase was greater in the Northeast (2.06 pp) and in municipalities with very low/low HDI (1.48 pp) and 100% family health strategy coverage (0.98 pp). Trends in the frequency of good quality health care during the first-week child check-up were favorable.

Resumo O objetivo deste estudo foi avaliar a tendência temporal da qualidade da atenção à saúde da criança na consulta da primeira semana de vida no nível da Atenção Primária à Saúde, segundo características dos municípios, do processo de trabalho das equipes e das usuárias responsáveis pelas crianças. Foram realizadas análises transversais com dados dos três ciclos do Programa Nacional de Melhoria do Acesso e da Qualidade (PMAQ) (2012, 2014 e 2018). Usuárias adultas com filhos de até dois anos foram entrevistadas. O desfecho foi a “boa qualidade da atenção à saúde na primeira semana de vida”. Foram realizadas análises descritivas e de tendência temporal por meio de regressão de mínimos quadrados ponderados por variância. A frequência de boa qualidade na consulta da primeira semana de vida foi 47,9% (IC95% 46,6-49,3) em 2012, 52,5% (IC95% 51,3-53,7) em 2014 e 53,3% (IC95% 52,2-54,4) em 2018, com um aumento anual de 0,73 ponto percentual (p<0,001). O aumento anual foi maior na região Nordeste (2,06 pp) e com IDH muito baixo/baixo (1,48 pp) e com 100% de cobertura de ESF (0,98 pp). Ao longo dos três ciclos do PMAQ-AB houve uma evolução favorável na frequência da boa qualidade na atenção à saúde na primeira semana de vida.