ABSTRACT: In Brazil, urea is the most used nitrogen (N) fertilizer to improve forage production. However, their excessive use can cause environmental impacts through N losses, such as ammonia (NH3) volatilization. Therefore, the current study adjusted and estimated the NH3 volatilization from urea applied on tropical pastures in three rainfall conditions using mathematical models. Data were collected from Marandu grass (Brachiaria brizantha) fertilized with 50 kg N ha-1 during wet, intermediate, and dry conditions. Ammonia volatilization was measured in five semi-open chambers for 21 days. The linear, quadratic, exponential, Gompertz, Groot, and Richards models were tested for fitting and estimating the NH3 volatilization. The Gompertz, Groot, and Richards models generated predictions similar to the observed data, with a high determination coefficient, indicating a better fit of these equations to data, with precision and accuracy. However, the Groot model was selected due to the lowest root mean square error of prediction (0.29 % total N lost as NH3). The greatest N loss as NH3 volatilization occurred in the wet, followed by intermediate and dry conditions (20.2, 17.0, and 11.3 % total N lost as NH3, respectively). Therefore, nitrogen losses as NH3 volatilization after application of 50 kg N ha-1, as urea source, are altered according to the weather conditions, reaching 20% of N added in the wet rainfall period. The Groot model is recommended for fitting and estimating the NH3 volatilization from urea applied on Marandu grass pastures in the wet and dry rainfall conditions.

RESUMO: No Brasil, a ureia é o fertilizante nitrogenado mais utilizado para melhorar a produção de forragem. No entanto, seu uso excessivo pode causar impactos ambientais por meio de perdas de nitrogênio (N), como a volatilização da amônia (NH3). Portanto, o objetivo do presente estudo foi ajustar a volatilização de NH3 da ureia aplicada em pastos tropicais em três condições de chuva utilizando modelos matemáticos. Dados foram coletados de pastos de capim-marandu (Brachiaria brizantha) adubado com 50 kg N ha-1 em condições úmidas, intermediárias e secas. A volatilização da NH3 foi medida em cinco câmaras semiabertas durante 21 dias. Os modelos, linear, quadrático, exponencial, Gompertz, Groot e Richards foram testados para ajuste e estimativa da volatilização do NH3. Os modelos de Gompertz, Groot e Richards geraram predições semelhantes aos dados observados, com alto coeficiente de determinação, indicando um melhor ajuste dessas equações aos dados, com acurácia e precisão. No entanto, o modelo Groot foi selecionado devido ao menor erro quadrático médio das predições (0,29% de N total perdido como NH3). A maior volatilização de NH3 ocorreu em condições climáticas úmida, seguido por intermediária e seca (20,2; 17,0 e 11,3% de N total perdido como NH3, respectivamente). Portanto, as perdas de N como volatilização de NH3 após a aplicação de 50 kg N ha-1, como fonte de ureia, são alteradas de acordo com as condições climáticas, atingindo a 20% do N adicionado nas condições úmidas. O modelo Groot é recomendado para ajuste e estimativa da volatilização de NH3 da ureia aplicada em pastos de capim Marandu em condições úmidas e secas.

Abstract Objective To analyze the impact of the COVID-19 pandemic on the residency of gynecology and obstetrics in São Paulo. Methods Cross-sectional study developed by representatives of residents of the Association of Gynecology and Obstetrics of the State of São Paulo (SOGESP, in the Portuguese acronym). Data were collected from questionnaires applied to gynecology and obstetrics residents registered on the SOGESP website in February 2022. The interviewees answered about the repercussions of the pandemic on medical residency and whether they had technical and psychological support during the period. Results A total of 247 questionnaires were collected from residents of gynecology and obstetrics. The residents had an age of 28.3 ± 3 years old, and most of them were female (88.4%). The displacement to COVID care was reported by 62.34% of the students, but only 35.6% reported completely adequate personal protective equipment and only 7.7% reported complete theoretical and technical instruction to support these patients. Almost all of the interviewees stated that the gynecology sector was the most affected. The majority of the interviewees considered that the second-year residents had the greatest loss, and more than half of the residents in the 1st and 2nd year said they wished to give up their residency during the pandemic. More than 80% of the residents reported online theoretical classes and/or presentation of articles, reinforcing the fact that virtual activities gained a greater space within the medical residency. Conclusion The pandemic impacted the residency in greater proportion in outpatient clinics and gynecological surgeries, also interfering with the physician's desire to continue with the program.

Resumo Objetivo Analisar o impacto pandemia de COVID-19 sobre a residência de ginecologia e obstetrícia do Estado de São Paulo. Métodos Estudo transversal desenvolvido por representantes dos residentes da Associação de Ginecologia e Obstetrícia do Estado de São Paulo (SOGESP). Foram coletados dados de questionários aplicados aos residentes de ginecologia e obstetrícia cadastrados no site da SOGESP em fevereiro de 2022. Os entrevistados responderam sobre repercussões da pandemia sobre a residência médica e se tiveram suporte técnico e psicológico durante o período. Resultados Foram levantados 247 questionários de residentes de ginecologia e obstetrícia. Os residentes apresentaram idade de 28,3 ± 3 anos, sendo a maioria do sexo feminino (88,4%). O deslocamento para “covidários” foi referido por 62,34% dos avaliados, porém somente 35,6% referiram equipamento de proteção individual completamente adequado e apenas 7,7% referiram instrução completa teórica e técnica para o suporte destes pacientes. Quase a totalidade dos entrevistados afirmou que o setor de ginecologia foi o mais afetado. A maioria dos entrevistados considerou que o os residentes do segundo ano foram os que tiveram maior prejuízo, sendo que mais da metade dos residentes do 1° e 2° ano afirmou ter desejado desistir da residência durante a pandemia. Mais de 80% dos residentes referiram aulas teóricas e/ou apresentação de artigos online, reforçando o fato de que as atividades virtuais ganharam um espaço maior dentro da residência médica. Conclusão A pandemia impactou nas residências em maior proporção nos ambulatórios e cirurgias ginecológicas, interferindo também sobre o desejo do médico de seguir com o programa.

Abstract Introduction The exposure of medical students to a full-time schedule that includes classes, extracurricular activities, patients’ lives responsibility, and great competition between classmates can interfere in emotional issues and in the sleep time. Objective The aim of the present study was to evaluate the sleep quality, and the incidence of anxiety and depression in medical school undergraduates as well as the relationship of these parameters with the intense use of technologies. Methods Fifty-five medical school undergraduates in their second year participated in the present study, answering questionnaires to evaluate sleep quality (Pittsburgh sleep quality index - PSQI), night-time use of technology (sleep time-related information and communication technology - STRICT), and signs of anxiety or depression (hospital anxiety and depression scale - HADS). Results The results showed 31 students (56.4%) with poor sleep quality (PSQI > 5). Based on the STRICT questionnaire, 36 (65.4%) of the participants referred to making use of technology at night-time; and 34 (61.8%) students had compatible anxiety score, while 14 (25.4%) had a compatible score for depression on the HADS questionnaire. There has been a correlation between poor sleep quality, the abuse of technologies before sleep time, and the presence of anxiety or depression. Conclusion The abuse of technology before sleep time reduced the sleep quality in the studied population, besides increasing the symptoms of anxiety and depression.

Abstract Sheep production systems face numerous challenges, which make decision-making a process fraught with risks and uncertainties. Modelling is a helpful tool in this respect, as it allows decision-makers to evaluate the behaviour of variables and their interrelationships, in addition to using previous or related information to predict results and simulate different scenarios. The advent of prediction models has made it possible to monitor the weight of an animal and determine the best time for its sale. Additionally, it allows producers to estimate the weights of the carcass and major marketable cuts before slaughter. All this information is directly associated with the profitability and success of the production activity. Therefore, in view of the different applications of mathematical models in production systems, this literature review examines concepts in modelling studies and the importance of using prediction models in meat sheep production. Furthermore, it addresses the practical application of modelling studies in predicting dry matter intake and carcass traits of meat sheep through correlated variables.

Resumen Los sistemas de producción ovina se enfrentan a numerosos desafíos, que hacen de la toma de decisiones un proceso lleno de riesgos e incertidumbres. En este sentido, la modelación es una herramienta útil, ya que permite a los tomadores de decisiones evaluar el comportamiento de las variables y sus interrelaciones, además de utilizar información previa o relacionada para predecir resultados y simular diferentes escenarios. El advenimiento de los modelos de predicción ha permitido monitorear el peso de un animal y determinar el mejor momento para su venta. Además, permite a los productores estimar los pesos de la canal y los principales cortes comercializables antes del sacrificio. Toda esta información está directamente asociada a la rentabilidad y el éxito de la actividad productiva. Por lo tanto, en vista de las diferentes aplicaciones de los modelos matemáticos en los sistemas de producción, esta revisión de la literatura examina los conceptos en los estudios de modelación y la importancia de utilizar modelos de predicción en la producción de ovinos de carne. Además, aborda la aplicación práctica de los estudios de modelación en la predicción de la ingesta de materia seca y los rasgos de la canal de ovinos de carne a través de variables correlacionadas.

RESUMO: O processo de desenvolvimento de uma nova cultivar de trigo requer tempo entre a obtenção da população base e a seleção da linhagem mais promissora. Estimar parâmetros genéticos com mais precisão nas primeiras gerações com vistas a antecipar a seleção significa avanços importantes para os programas de melhoramento de trigo. Assim, o presente estudo estima os parâmetros genéticos de populações F2 de trigo tropical e o ganho genético da seleção via abordagem Bayesiana. Para tanto, os autores avaliaram a produtividade de grãos por parcela de 34 populações F2 de trigo tropical. A abordagem Bayesiana proporcionou um ajuste adequado ao modelo, estimando parâmetros genéticos dentro do espaço paramétrico. A herdabilidade (h2) foi de 0,51. Dentre as selecionadas, 11 populações F2 obtiveram desempenho superior às cultivares controle, com ganho genético de seleção de 7,80%. As seguintes populações foram as mais promissoras: Tbio Sossego/CD 1303, CD 1303/Tbio Ponteiro, BRS 254/CD 1303, Tbio Duque/Tbio Aton e Tbio Aton/CD 1303. A inferência Bayesiana pode ser usada para melhorar significativamente programas de melhoramento de trigo tropical.

ABSTRACT: The development process of a new wheat cultivar requires time between obtaining the base population and selecting the most promising line. Estimating genetic parameters more accurately in early generations with a view to anticipating selection means important advances for wheat breeding programs. Thus, the present study estimated the genetic parameters of F2 populations of tropical wheat and the genetic gain from selection via the Bayesian approach. To this end, the authors assessed the grain yield per plot of 34 F2 populations of tropical wheat. The Bayesian approach provided an adequate fit to the model, estimating genetic parameters within the parametric space. Heritability (h2) was 0.51. Among those selected, 11 F2 populations performed better than the control cultivars, with genetic gain of 7.80%. The following populations were the most promising: TbioSossego/CD 1303, CD 1303/TbioPonteiro, BRS 254/CD 1303, Tbio Duque/Tbio Aton, and Tbio Aton/CD 1303. Bayesian inference can be used to significantly improve tropical wheat breeding programs.

ABSTRACT Among the multi-trait models selected to study several traits and environments jointly, the Bayesian framework has been a preferred tool when constructing a more complex and biologically realistic model. In most cases, non-informative prior distributions are adopted in studies using the Bayesian approach. However, the Bayesian approach presents more accurate estimates when informative prior distributions are used. The present study was developed to evaluate the efficiency and applicability of multi-trait multi-environment (MTME) models within a Bayesian framework utilizing a strategy for eliciting informative prior distribution using previous data on rice. The study involved data pertaining to rice (Oryza sativa L.) genotypes in three environments and five crop seasons (2010/2011 until 2014/2015) for the following traits: grain yield (GY), flowering in days (FLOR) and plant height (PH). Variance components, genetic and non-genetic parameters were estimated using the Bayesian method. In general, the informative prior distribution in Bayesian MTME models provided higher estimates of individual narrow-sense heritability and variance components, as well as minor lengths for the highest probability density interval (HPD), compared to their respective non-informative prior distribution analyses. More informative prior distributions make it possible to detect genetic correlations between traits, which cannot be achieved with non-informative prior distributions. Therefore, this mechanism presented to update knowledge for an elicitation of an informative prior distribution can be efficiently applied in rice breeding programs.

ABSTRACT Identifying Coffea arabica cultivars that are more efficient in the use of nitrogen is an important strategy and a necessity in the context of environmental and economic impacts attributed to excessive nitrogen fertilization. Although Coffea arabica breeding data have a multi-trait structure, they are often analyzed under a single trait structure. Thus, the objectives of this study were to use a Bayesian multitrait model, to estimate heritability in the broad sense, and to select arabica coffee cultivars with better genetic potential (desirable agronomic traits) in nitrogen-restricted cultivation. The experiment was carried out in a greenhouse with 20 arabica coffee cultivars grown in a nutrient solution with low-nitrogen content (1.5 mM). The experimental design used was in randomized blocks with three replications. Six agromorphological traits of the arabica coffee breeding program and five nutritional efficiency indices were used. The Markov Chain Monte Carlo algorithm was used to estimate genetic parameters and genetic values. The agromorphological traits were considered highly heritable, with a credibility interval (95% probability): H2 = 0.9538 – 5.89E-01. The Bayesian multitrait model presents an adequate strategy for the genetic improvement of arabica coffee grown in low-nitrogen concentrations. Coffee arabica cultivars Icatu Precoce 3282, Icatu Vermelho IAC 4045, Acaiá Cerrado MG 1474, Tupi IAC 1669-33, Catucaí 785/15, Caturra Vermelho and Obatã IAC 1669/20 demonstrated greater potential for cultivation in low-nitrogen concentration.

Abstract: The present study thematizes racism in class society and aims to analyze the consequences of racial inequalities in the covid-19 pandemic. Therefore, the Historical-Dialectical Materialism method and a qualitative approach were used. In this way, a bibliographic and documentary research was carried out, in addition to a mapping work based on secondary data from the Brazilian Institute of Geography and Statistics (IBGE) of 2019, Atlas of Violence of 2020 made by the Institute of Applied Economic Research (IPEA) and the Special Bulletin 20 November 2021 of the Inter-union Department of Statistics and Socioeconomic Studies (DIEESE) to dialogue with the reality of Afro-Brazilians in a pandemic scenario. From the results of the study, we highlight that racism has been a structuring axis of Brazilian society even in a post-abolitionist phase; that the Racial Question has been one of the expressions of the Social Question in the society of Capital, in such a way that inequalities are connected in contemporaneity; and, that the pandemic accentuated racial inequalities in Brazil.

Resumo: O presente estudo tematiza o racismo na sociedade de classes e tem como objetivo analisar os desdobramentos das desigualdades raciais na pandemia da Covid-19. Logo, utilizou-se o método materialismo histórico-dialético e uma abordagem qualitativa. Dessa forma, foi realizada uma pesquisa bibliográfica e documental, além de um trabalho de mapeamento a partir dos dados secundários do Instituto Brasileiro de Geografia e Estatística (IBGE) de 2019; Atlas da violência de 2020, elaborado pelo Instituto de Pesquisa Econômica Aplicada (IPEA); e o Boletim especial 20 de novembro de 2021, do Departamento Intersindical de Estatística e Estudos Socioeconômicos (DIEESE), para dialogar com a realidade dos afro-brasileiros em cenário pandêmico. Dos resultados do estudo, destacamos: que o racismo tem sido um eixo estruturante da sociedade brasileira mesmo numa fase pós-abolicionista; e que a questão racial tem sido uma das expressões da questão social na sociedade do capital, de tal modo que as desigualdades são conexas na contemporaneidade; e ainda, que a pandemia acentuou as desigualdades raciais no Brasil.

Abstract This study evaluated the bioactive potential of a macro-porous chitosan scaffold incorporated with calcium hydroxide (CH-Ca) and functionalized with bioactive doses of simvastatin (SV) for bone tissue regeneration. Initially, the bioactive dose of SV in osteoblastic cells (SAOS-2) was determined. For the direct contact experiment, SAOS-2 cells were plated on scaffolds to assess cell viability and osteogenic differentiation. The second assay was performed at a distance using extracts from scaffolds incubated in culture medium to assess the effect of conditioned medium on viability and osteogenic differentiation. The initial screening showed that 1 μM SV presented the best biostimulating effects, and this dose was selected for incorporation into the CH-Ca and pure chitosan (CH) scaffolds. The cells remained viable throughout the direct contact experiment, with the greatest cell density in the CH-Ca and CH-Ca-SV scaffolds because of their higher porosity. The CH-Ca-SV scaffold showed the most intense bio-stimulating effect in assays in the presence and absence of osteogenic medium, leading to an increased deposition of mineralized matrix. There was an increase in the viability of cells exposed to the extracts for CH-Ca, CH-SV, and CH-Ca-SV during the one-day period. There was an increase in ALP activity in the CH-Ca and CH-Ca-SV; however, the CH-Ca-SV scaffold resulted in an intense increase in the deposition of mineralized nodules, approximately 56.4% at 7 days and 117% at 14 days, compared with CH (control). In conclusion, functionalization of the CH-Ca scaffold with SV promoted an increase in bioactivity, presenting a promising option for bone tissue regeneration.

ABSTRACT Plant resistance is an important tactic within the precepts of Integrated Pest Management, and the existence of grain sorghum hybrids with multiple insect resistance could benefit crop management and sustainability. This study evaluated the susceptibility of 30 grain-sorghum hybrids to three major pests, namely, fall armyworm (FAW) Spodoptera frugiperda, sugarcane borer (SCB) Diatraea saccharalis, and green-belly stink bug (GBS) Diceraeus melacanthus. The hybrids were cultivated and experiments with each insect species were conducted separately in a greenhouse. For FAW, visual injury assessments were performed on plants 7 and 14 days after infestation (DAI). For SCB, insect presence and injury were assessed 40 DAI. For GBS, the plants were evaluated using a damage rating scale 12, 19, and 26 DAI. Cluster analysis allowed separating the grain sorghum hybrids into groups regarding the levels of resistance to each pest. Hybrid BRS373 stood out as moderately resistant to FAW; AG1090, 80G20, BRAVO, BRS373, AG1615, and IG220 were the most promising for SCB; and for GBS, hybrids 50A40, A9735R, JADE, ENFORCER, BUSTER, 50A10, and IG244 were the most nominated. This information will significantly aid sorghum breeding programs focused on developing commercial hybrids that comprise both insect-resistance and high-yield characteristics. However, further research should evaluate potential chemical and morphological plant traits underlying the lower levels of susceptibility to FAW, SCB, and GBS found in the selected sorghum hybrids.

Abstract To analyze the design of educational governance for Basic Education that materialized in the first year of the Covid-19 pandemic in Amazonas, the article resumes and analyzes the decision-making of the public power on the municipal and state education systems of the capital and state between March 2020 and February 2021. Based on the Sociology of Public Action and a qualitative approach, the study that serves as the basis for this article – developed by researchers in the field of Education at the Federal University of Amazonas, based on an integrative review of the specialized literature, mapping and analysis of the actions of the education departments of Manaus and Amazonas – reconstructed the consolidated paths in the educational field in one of the epicenters of the pandemic in the country. The data reveal the complex network of public and private agents that engender the governance investigated here, the tensions between the comings and goings around the resumption of face-to-face classes, as well as alternative teaching models for the pandemic scenario and the deepening of public-private partnerships.

Resumen Con el objetivo de analizar el diseño de la gobernanza educativa para la Educación Básica, que se materializó en el primer año de la pandemia de la Covid-19, en Amazonas, el artículo retoma y analiza la toma de decisiones del poder público sobre las redes municipales y estatales de docencia en la capital y en el estado, entre marzo de 2020 y febrero de 2021. Con base en la Sociología de la Acción Pública, y un enfoque cualitativo, el estudio que sirve de base a este artículo –realizado por investigadores del área de Educación en la Universidad Federal de Amazonas, a partir de una revisión integradora de la literatura especializada, mapeo y análisis de las acciones de los departamentos de educación de Manaus y Amazonas – reconstruyeron los caminos consolidados en el campo educativo en uno de los epicentros de la pandemia en el país. Los datos revelan la compleja trama de agentes públicos y privados que engendran la gobernanza aquí investigada, las tensiones entre los vaivenes en torno a la reanudación de las clases presenciales, así como los modelos alternativos de enseñanza para el escenario de la pandemia y la profundización de las alianzas público-privadas.

Resumo Com o objetivo de analisar o desenho da governança educacional para a Educação Básica, que se materializou no primeiro ano da pandemia de Covid-19, no Amazonas, o artigo retoma e analisa as tomadas de decisões do poder público sobre as redes municipal e estadual de ensino da capital e do estado, entre março de 2020 e fevereiro de 2021. A partir da Sociologia da Ação Pública, e de uma abordagem qualitativa, o estudo que serve de base para esse artigo – levado a cabo por pesquisadoras da área da Educação da Universidade Federal do Amazonas, a partir de uma revisão integrativa da literatura especializada, de mapeamento e de análise das ações das secretarias de Educação de Manaus e do Amazonas – reconstruiu os caminhos consolidados no campo educacional em um dos epicentros da pandemia no país. Os dados são reveladores da complexa teia de agentes públicos e privados que engendram a governança aqui investigada, das tensões entre as idas e as vindas em torno da retomada das aulas presenciais, bem como dos modelos de ensino alternativos para o cenário pandêmico e do aprofundamento das parcerias público-privadas.

Abstract Objective To analyze the trend of suicide mortality in the state of Espirito Santo and its Mountain Region from 1996 to 2020. Methods Descriptive and analytical time series study with consolidated data on deaths by suicide in the population over 15 years old obtained from the Mortality Information System. The units of analysis were the state of Espirito Santo and its Mountain Region. The trend analysis was verified by Prais-Winsten regression and by calculating the annual percentage change. Results A total of 3922 deaths by suicide were reported in Espirito Santo and of these, 525 in the mountain Region. The trend of suicide mortality in the state was increasing in the general population over 15 years old (APC= 5.1; 95%CI= 0.28-9.92; p=0.039). The mortality rate continued to grow among the female population, both in relation to the state (APC= 6.5; 95%CI= 1.55-14.46; p=0.012) and in the mountain region (APC= 15.2; 95%CI= 1.21-29.20; p=0.035). Mortality increased in the age group from 30 to 59 years old in the state (APC= 3.4; 95%CI= 0.62-6.10; p=0.018) and in the Mountain Region (APC= 2.9; 95%CI= 2.02-3.86; p<0.001). Conclusion The suicide trend was growing in the general population of the state of Espirito Santo and its Mountain Region among young and female adults. The relevance of self-inflicted violence verified in the rates analyzed in this study points to the need to use preventive strategies, especially among women.

Resumen Objetivo Analizar la tendencia de la mortalidad por suicidio en el estado de Espírito Santo y en su Región Serrana en el período de 1996 a 2020. Métodos Estudio descriptivo y analítico de serie temporal con datos consolidados de las muertes por suicidio en la población mayor de 15 años obtenidos del Sistema de Información sobre Mortalidad. Las unidades de análisis fueron el estado de Espírito Santo y su Región Serrana. El análisis de la tendencia se verificó por regresión de Prais-Winsten y por cálculo de la variación porcentual anual. Resultados Se notificaron 3.922 muertes por suicidio en Espírito Santo, de las cuales 525 fueron en la Región Serrana. La tendencia de la mortalidad por suicidio en el estado fue creciente en la población general mayor de 15 años (APC= 5,1; IC95 %= 0,28-9,92; p=0,039). La tendencia de la mortalidad se mantuvo creciente en la población femenina, tanto con relación al estado (APC= 6;5; IC95 %= 1,55-14,46; p=0,012) como en la Región Serrana (APC= 15,2; IC95 %= 1,21-29,20; p=0,035). La mortalidad fue creciente en el grupo de edad de 30 a 59 años en el estado (APC= 3,4; IC95 %= 0,62-6,10; p=0,018) y en la Región Serrana (APC= 2,9; IC95 %= 2,02-3,86; p <0,001). Conclusión La tendencia fue creciente en la población general del estado de Espírito Santo y en su Región Serrana en adultos jóvenes y de sexo femenino. La relevancia de la violencia autoprovocada verificada en los índices analizados en este estudio indica la necesidad de emplear estrategias preventivas, específicamente en mujeres.

Resumo Objetivo Analisar a tendência da mortalidade por suicídio no estado do Espírito Santo e em sua Região Serrana no período de 1996 a 2020. Métodos Estudo descritivo e analítico de série temporal com dados consolidados dos óbitos por suicídio na população acima de 15 anos de idade obtidos no Sistema de Informações sobre Mortalidade. As unidades de análise foram o estado do Espírito Santo e sua Região Serrana. A análise da tendência foi verificada pela regressão de Prais-Winsten e pelo cálculo da variação percentual anual. Resultados Foram notificados 3.922 óbitos por suicídio no Espírito Santo e, destes, 525 na Região Serrana. A tendência da mortalidade por suicídio no estado foi crescente na população geral acima de 15 anos (APC= 5,1; IC95%= 0,28-9,92; p=0,039). A tendência da mortalidade se manteve crescente entre a população feminina, tanto em relação ao estado (APC= 6;5; IC95%= 1,55-14,46; p=0,012) como na região serrana (APC= 15,2; IC95%= 1,21-29,20; p=0,035). A mortalidade foi crescente na faixa etária de 30 a 59 anos no estado (APC= 3,4; IC95%= 0,62-6,10; p=0,018) e na Região Serrana (APC= 2,9; IC95%= 2,02-3,86; p <0,001). Conclusão A tendência foi crescente na população geral do estado do Espírito Santo e em sua Região Serrana entre adultos jovens e do sexo feminino. A relevância da violência autoprovocada verificada nas taxas analisadas neste estudo aponta para a necessidade do emprego de estratégias preventivas, especialmente entre as mulheres.

ABSTRACT The effects of diets containing oilseeds were measured to evaluate the productive and economic parameters in the finishing of young, feedlot Nellore bulls. Twenty-four young Nellore bulls were used, with an initial body weight (BW) of 311.46±0.37 kg and 24 months of age, distributed into individual stalls ( 4 × 20 m) in a completely randomized design, totaling four treatments with six repetitions per treatment. Four diets (control, based on corn and soybean meal, and three diets containing cottonseed, soybean, and sunflower) were evaluated. Feed and orts were measured daily to calculate intake and costs. The dry matter intake of the control group was higher than soybean (10.64 kg/day), cotton (9.88 kg/day), and sunflower (9.30 kg/day) treatments, respectively. The cottonseed treatment showed the highest average neutral detergent fiber intake. There was a dietary effect of diets on average daily gain, total weight gain, and final weight. The soybean treatment showed the highest performance, total gain (232.55 kg), and final weight (544.38 kg). Oilseed intake can modify the fatty acids profile in the meat, decreasing its saturated fatty acid content. Whole soybean seed favors performance, improves feed efficiency, fatty acid profile, and fat distribution in the carcass, and can reduce production costs.

Abstract This study was conducted to test the significance of adding row and column factors in the frequentist and Bayesian models used in the evaluation of a population of Passiflora edulis, as well as selecting promising genotypes to form the next generation. The following parameters were evaluated: number of fruits, yield, fruit weight, transverse fruit diameter, longitudinal fruit diameter, pulp percentage, skin thickness and total soluble solids. For the Bayesian model, two priors were considered, namely, inverse gamma and a priori distribution with extended parameters. The model with a priori distribution with extended parameters showed lower root mean square error and higher correlation coefficient between observed and predicted values than the inverse gamma model. Furthermore, for a selection intensity of 37%, the mixed and Bayesian models selected practically the same progenies in both experiments. The use of the 5-fold cross-validation technique indicated that both tested models were efficient.

ABSTRACT Purpose: After partial hepatectomy (PH), the remaining liver (RL) undergoes regenerative response proportional to the host. Limited literature exists on hepatic viability after tissue injury during hypothermic preservation. Spectroscopy measures cellular fluorescence and is explored for tissue characterization and parameter investigation. This study aimed to assess fluorescence analysis (spectroscopy) in evaluating liver viability and its relationship with hepatic tissue regeneration 24 hours after PH. Additionally, we analyzed liver regeneration in RL after 70% partial hepatectomy under hypothermic conditions with laser irradiation. Methods: Fifty-six Wistar rats were divided into four groups: total non-perfused liver (control), total perfused liver, partial hepatectomy “in situ”, and partial hepatectomy “ex situ”. Tissue analysis was performed at 0 and 24 hours using spectroscopy with laser devices emitting at 532 (green) and 405 nm (violet). Results: Spectroscopy identified tissue viability based on consistent results with Ki67 staining. The fluorescence spectra and Ki67 analysis displayed similar patterns, linking proliferative activity and absorption intensity. Conclusions: Fluorescence spectroscopy proves to be promising for real-time analysis of cellular activity and viability. Metabolic activity was observed in groups of live animals and hypothermically preserved samples, indicating cellular function even under blood deprivation and hypothermic conditions.