The main objective of this paper is to introduce an introductory systematization of a pedagogical conception, developed from the Viktor Frankl’s thought, so that it can move towards a foundation of educational activity. Firstly, we present the anthropological, epistemological and axiological foundations of Logotherapy and Existential Analysis, theory created by the Austrian author. Then, we discuss how these foundations can guide educational activity from the following topics: aims of education, role of the school, learning assumptions, teaching content, methods, teacher-student relationship. In short, the purpose of this pedagogical proposal is to support the person to develop an autonomous life, anchored in meaning and values, and to discover and carry out a meaningful life project that contributes to something in the world.

O objetivo central deste artigo é sistematizar introdutoriamente uma concepção pedagógica, elaborada a partir do pensamento de Viktor Frankl, de modo que possa caminhar para uma fundamentação da atividade educativa. Primeiramente, apresentamos os fundamentos antropológicos, epistemológicos e axiológicos da Logoterapia e Análise Existencial, teoria criada pelo autor austríaco. Em seguida, discutimos como esses fundamentos podem orientar a atividade educativa a partir dos seguintes tópicos: objetivos da educação, papel da escola, pressupostos de aprendizagem, conteúdos de ensino, métodos, relação professor-estudante. Em suma, a finalidade dessa proposta pedagógica é apoiar a pessoa para desenvolver uma vida autônoma, ancorada em sentido e valores, e para descobrir e realizar um projeto de vida significativo que contribua com algo no mundo.

Abstract The recovery of metals from minerals through alternative processes is appropriate for the reduction of pollutants produced in foundries and traditional operations; the leaching of metals with the use of chemical reagents at low concentrations allows the reuse of the solutions, as well as the reduction of problems in the recycling of the solutions. Leaching with organic reagents at room temperature reduces the issues in the generation of gases and consumption of reagents, which is why it turns out to be an option for obtaining metals from minerals. This work shows an alternative for lead recovery by leaching a galena mineral using sodium citrate in a concentration of 0.2 M at room temperature. The effect of pH in acid, neutral, and alkaline mediums is evaluated, where recovery of 99.9% of lead in alkaline media is achieved.

Resumen La recuperación de metales a partir de minerales mediante procesos alternativos es apropiada para la reducción de contaminantes producidos en fundiciones y operaciones tradicionales; la lixiviación de metales con el uso de reactivos químicos a bajas concentraciones permite la reutilización de las soluciones, así como la reducción de problemas en el reciclaje de las soluciones. La lixiviación con reactivos orgánicos a temperatura ambiente reduce los problemas de generación de gases y consumo de reactivos, por lo que resulta ser una opción para la obtención de metales a partir de minerales. Este trabajo presenta una alternativa para la recuperación de plomo mediante la lixiviación de un mineral de galena utilizando citrato de sodio en una concentración de 0.2 M a temperatura ambiente. Se evalúa el efecto del pH en medio ácido, neutro y alcalino, donde se logra recuperar el 99.9% de plomo en medio alcalino.

Abstract The objective of this study was to develop a viable and low-cost model of voluntary physical exercise that could be applied to studies on metabolism and behavior. 40 male zebrafish (Danio rerio) were studied, divided into two groups: control and voluntary physical exercise. The model consisted of two aquariums connected by a translucent tube and a video camera on the side to measure physical exercise parameters of the animals. The animals showed higher acceleration and maximum speed and had a higher frequency of activity in the light period. In this model of voluntary physical exercise, we observed better performance in locomotor assessment tests, which was not accompanied by increased anxiety or changes in biochemical parameters related to lipid metabolism. Zebrafish responded positively to voluntary physical exercise and this model appears to be a good option for further studies.

The aim of this investigation was to study and evaluate the fracture toughness (KICV) of an AISI M3:2 high speed steel that was prepared by powder metallurgical processing, which consisted of uniaxial cold compaction of irregularly shaped water atomized powders, without and with 0.3% of carbon in the form of graphite, followed by vacuum sintering to obtain compacts with densities close to its theoretical value. The sintered steels were then hardened by austenitizing, quenching and triple tempering. Chevron fracture toughness test samples were prepared from the compacts and the tests conducted to determine KICV. The microstructures of the specimens were examined by scanning electron microscopy (SEM), and the composition of the phases determined by x-ray diffraction analysis (XRD). The sizes of the primary carbides and of the austenite grains were determined using Quantikov digital analysis software. No significant difference in fracture toughness (KICV) between the two high speed steels AISI M3:2, austenitized at the different temperatures, was observed.

ABSTRACT: This work aims to investigate the work and professional development of Brazilian teachers during emergency remote teaching in the COVID-19 pandemic, considering aspects such as working conditions, teaching-learning, and mental health. A sample of 364 basic education teachers in Brazil was assessed using self-report instruments considering sociodemographic data, working conditions, aspects related to teaching work and teaching learning (activities, knowledge and teacher education), mental health, and meaning in life. The results showed that changes in teaching work occur amid the absence or limited experience of most teachers with online teaching and/or the use of digital technology, in addition to the lack of adequate support and working conditions. The main tasks were mediated by technology, and didactic knowledge played a fundamental role in this context. The education offered to teachers by the institutions was largely insufficient, causing the need for complementary (self)education. Experiential knowledge has been shown to be fundamental in teaching and learning. Finally, mental health was shown to play a crucial role in this professional development process, in addition to demonstrating a positive correlation with the presence of meaning in life. The implications for the professional development of teachers are discussed.

RESUMEN: Este trabajo tiene como objetivo investigar la actuación y desarrollo profesional de profesores brasileños durante la enseñanza remota de emergencia en la pandemia COVID 19, considerando aspectos como las condiciones de trabajo, aprendizajes de los docentes y su salud mental. Una muestra de 364 profesores de educación básica en Brasil fue evaluada a partir de instrumentos de autodescripción considerando datos socio demográficos, condiciones de trabajo, aspectos relativos a la actuación del docente y el aprendizaje de la docencia (actividades, saberes y formación profesional), salud mental y sentido de la vida. Los resultados indican que los cambios en el trabajo docente se dan en medio de la ausencia o poca experiencia de la mayoría de los profesores con la enseñanza online y/o uso de tecnología digital, además de la falta de apoyo y condiciones laborales adecuadas. Las principales tareas estuvieron conciliadas por la tecnología y los saberes didácticos jugó un papel fundamental en este contexto. La formación ofrecida a los profesores por parte de las instituciones educativas fue en la mayoría de los casos insuficiente, provocando la necesidad de una autocapacitación complementaria. Los saberes experienciales demostraron ser fundamentales en la enseñanza docente. Finalmente, Se ha demostrado que la salud mental juega un papel crucial un papel crucial en este proceso de desarrollo profesional, además de demostrar una correlación positiva con la presencia de sentido en la vida. Implicaciones para el desarrollo profesional docente son discutidas.

RESUMO: Este trabalho tem como objetivo investigar a atuação e desenvolvimento profissional de professores brasileiros durante o ensino remoto emergencial na pandemia de covid-19, considerando aspectos como condições de trabalho, de aprendizagem da docência e da saúde mental. Uma amostra de 364 professores da Educação Básica no Brasil foi avaliada a partir de instrumentos de autorrelato considerando dados sociodemográficos, condições de trabalho, aspectos relativos à atuação docente e aprendizado da docência (atividades, saberes e formação docentes), saúde mental e sentido da vida. Os resultados apontaram que as mudanças no trabalho docente ocorrem em meio à ausência ou pouca experiência da maioria dos professores com ensino on-line e/ou com uso de tecnologia digital, além da falta de apoio e condições de trabalho adequados. As principais tarefas foram mediadas por tecnologia e os saberes didáticos tiveram um papel fundamental neste contexto. A formação oferecida aos professores pelas instituições educativas foi insuficiente em grande parte, provocando a necessidade de (auto)formações complementares. Os saberes experienciais demonstraram ser fundamentais na aprendizagem da docência. Finalmente, a saúde mental demonstrou ter um papel crucial nesse processo de desenvolvimento profissional, além de demonstrar uma correlação positiva com a presença de sentido na vida. Implicações para o desenvolvimento profissional docente são discutidas.

The article presents a synthesis of the data obtained through a qualitative study, of an exploratory nature, with the objective of investigating the professional development of teachers in emergency remote teaching during the COVID-19 pandemic, in the second half of the year 2020, including working conditions, teaching learning and mental health. The participants (n=364) are basic education teachers from different parts of Brazil who answered online questionnaires. The results point to precarious conditions in the teaching work amidst the absence/little experience with the use of digital technology in the teaching-learning process and the training offered by educational institutions was largely insufficient, which led to the search for complementation by own account. The teacher's experience and didactic knowledge as planning proved to be fundamental to deal with the challenges of this scenario. Mental health has been shown to play a crucial role in professional development, in addition to demonstrating a positive correlation with the presence of meaning in life.

O artigo apresenta síntese dos dados obtidos por meio de um estudo qualitativo, de natureza exploratória, com o objetivo de investigar o desenvolvimento docente no ensino remoto emergencial durante a pandemia de COVID-19, no segundo semestre de 2020, incluindo as condições de trabalho, aprendizagem da docência e saúde mental. Os participantes=364) são professores da educação básica de diversas partes do Brasil que atendem on-line. Os resultados apontam condições precárias no trabalho docente em meio a ausência/pouca experiência com o uso de tecnologia digital no processo de ensino-aprendizagem e formação de ensino-aprendizagem foram, em grande parte, insuficientemente, o que levou à busca de complementações por conta própria. A do professor saberes didáticos como o planejamento desse cenário e fundamentos para lidar com os cenários. A saúde mental tem um papel crucial no desenvolvimento profissional, demonstrando uma importância positiva com a vida além do sentido.

ABSTRACT The management of human talent are vital processes for the growth and development of a corporation, people being the reason for being of an organization, their expertise and the decisions they make daily are those that generate a competitive advantage in the world of work. The purpose of the following research is to establish the challenges of human talent in time of pandemic (COVID- 19). For which a descriptive scope research was carried out. This analysis focused on identifying the current state and trends in talent management. In this sense, it could be concluded that the Artificial Intelligence used through digital applications effectively in the processes of recruitment, selection of personnel, recruitment, performance evaluation, training and programs: cost reduction, increased productivity and speed of response.

RESUMEN La gestión del talento humano son procesos vitales para el crecimiento y desarrollo de una corporación, siendo las personas la razón de ser de una organización; el expertiz y las decisiones que toman a diario son las que generan una ventaja competitiva en el mundo laboral. El propósito de la siguiente investigación es establecer los desafíos del talento humano en tiempo de pandemia (COVID - 19). Para lo cual se realizó una investigación de alcance descriptivo. Dicho análisis se enfocó en identificar el estado actual y las tendencias de la gestión del talento. En este sentido, se pudo concluir que la Inteligencia Artificial utilizada mediante aplicaciones digitales de manera efectiva en los procesos de reclutamiento, selección de personal, evaluación desempeño, capacitación y programas de liderazgo genera en las organizaciones: reducción de costos, aumento de la productividad y velocidad de respuesta.

Summary: The development and production of cabbage (Brassica oleracea var. Royal vantage) in a greenhouse, under different osmotic pressures of the Steiner nutrient solution and biofertlized with bacterial consortiums, were evaluated. A 4 × 3 factorial design was established, where the factors were four levels of osmotic pressure (0.18, 0.36, 0.54 atm and a control without nutrient solution), and two bacterial consortia: Azospirillum brasilense + Acinetobacter calcoaceticus (AA) and Raoultella terrigena + Chromobacterium violaceum (RC), and an uninoculated control. Six repetitions were established for each treatment. Seeds inoculated with the consortium AA had the highest emergence percentage (100%), as well as the highest emergence rate (20.5), compared with the consortium RC and the non-inoculated plants. Inoculation with the consortium AA and the osmotic pressure of 0.54 atm produced taller plants (60-65%), and a stem with a larger diameter (35-46%). The weight of the fresh biomass and the accumulation of dry material doubled in the inoculated plants compared to the non-inoculated ones. A higher concentration of K was observed in plants inoculated with AA and RC (20‑35% and 25-45%, respectively) compared to non-inoculated plants. The nitrate concentration in the plants increased between 200-350% and 60-230% with the inoculation of consortia AA and RC, respectively. The P concentration increased between 200-500% with the consortium AA and between 100-400% with the consortium RC. Inoculation with the consortia AA and RC, at osmotic pressure of 0.54 atm, induced the greatest development of the cabbage heads (classified as 5 and 4, respectively). It is concluded that cabbage, under moderate mineral fertilization in a greenhouse, responds favorably to the inoculation of plant growth promoting bacteria.

Resumen: Se evaluó el desarrollo y producción de la col (Brassica oleracea var. Royal vantage) en invernadero, bajo diferentes presiones osmóticas de la solución nutritiva Steiner y biofertlizada con consorcios bacterianos. Se estableció un diseño factorial 4 × 3, donde los factores fueron cuatro niveles de presión osmótica (0.18, 0.36, 0.54 atm y un testigo sin solución nutritiva), y dos consorcios bacterianos: Azospirillum brasiliense + Acinetobacter calcoaceticus (AA) y Raoultella terrigena + Chromobacterium violaceum (RC), y un testigo sin inocular. Se establecieron seis repeticiones por cada tratamiento. Las semillas inoculadas con el consorcio AA presentaron el mayor porcentaje de emergencia (100%), así como la tasa de emergencia más alta (20.5), en comparación con consorcio RC y las plantas no inoculadas. La inoculación con el consorcio AA y la presión osmótica de 0.54 atm produjeron plantas más altas (60-65%), y un tallo con mayor diámetro (35-46%). El peso de la biomasa fresca y la acumulación de materia seca se duplicaron en las plantas inoculadas con respecto a las no inoculadas. Se observó mayor concentración de K en plantas inoculadas con AA y RC (20-35% y 25-45%, respectivamente) respecto a las plantas no inoculadas. La concentración de nitratos en las plantas se incrementó entre 200-350% y 60-230% con la inoculación de los consorcios AA y RC, respectivamente. La concentración de P se incrementó entre 200-500% con el consorcio AA y entre 100-400% con el consorcio RC. La inoculación con los consorcios AA y RC, a presión osmótica de 0.54 atm, indujo el mayor desarrollo de las cabezas de la col (clasificadas como 5 y 4, respectivamente). Se concluye que la col, bajo fertilización mineral moderada en invernadero, responde favorablemente a la inoculación de bacterias promotoras de crecimiento vegetal.

RESUMEN Objetivos. Determinar la existencia de un estrés calórico en pollos de engorda y evaluar la efectividad de la suplementación con un producto orgánico de Cr en la disminución de este. Materiales y Métodos. Se determinó la existencia de un estrés calórico mediante la medición del comportamiento de la temperatura y la humedad relativa durante el experimento. Estos indicadores se registraron diariamente, con frecuencia de una hora, utilizando termohigrómetros digitales. Se utilizaron 45 pollos de engorda Ross 308 sexados machos, desde 1 d de edad, provenientes de un experimento de comportamiento productivo con 300 animales. Estos se distribuyeron en tres tratamientos (control, 200 y 400 ppbCr/ kg de dieta) según un diseño completamente aleatorizado, con 4 repeticiones de 25 pollos cada una. Al finalizar el ciclo productivo se determinó la concentración de cortisol en suero sanguíneo de 15 animales por tratamiento, como indicador de estrés. Cada animal constituyó una unidad experimental. Para el análisis de los resultados, se utilizó el paquete estadístico computarizado INFOSTAT. Resultados. Los valores del índice de confort de temperatura y humedad durante los últimos 32 días de duración de la prueba oscilaron entre 112.53 y 115.26. Las concentraciones promedio de cortisol para los tres tratamientos evaluados fueron de 9.45, 8.91 y 7.66 nmol/L, respectivamente, sin mostrar diferencias significativas entre ellos. Conclusiones. El producto orgánico de Cr fue efectivo en la reducción del estrés calórico al disminuir la concentración de cortisol, aunque no significativamente, en suero sanguíneo de los pollos de engorda. Se ratificó la existencia de un estrés generado por calor durante la realización del experimento.

ABSTRACT Objective. Determinate the existence of a heat stress in broilers and evaluate the effectiveness of the supplementation with an organic Cr product for decreasing or heat stress in broilers. Materials and Methods. The existence of heat stress was determined by measuring temperature and relative humidity during the experiment. These indicators were daily registered, every 1 hour, with the use of digital thermo-hygrometers. An amount of 45 male Ross 308 broilers was used, from 1 day of age, belonging to a productive performance experiment with 300 animals. They were distributed in three treatments (control, 200 and 400 ppbCr/kg of diet) according to a completely randomized design, with 4 repetitions of 25 animals each. At the end of this productive cycle, cortisol concentration in blood serum was determined in 15 animals per treatment, as an indicator of stress. Every animal constituted an experimental unit. For the analysis of results, INFOSTAT statistical package was used. Results. Temperature-humidity index values during the last 32 days of the experiment ranged between 112.53 and 115.26. Mean values of cortisol concentration were 9.45, 8.91 and 7.66 nmol/L, for the three evaluated treatments respectively. This decrease was not statistically significant. Conclusions. The organic Cr product was effective for decreasing heat stress by reducing cortisol concentration, although not significant, in blood serum of broilers. The existence of stress generated by heat during the experiment was confirmed.

ABSTRACT Phytogenic additives are organic molecules that also improve ruminal fermentation, turning the supplemented individuals into more productive animals, without damage the population welfare. The objective of this study was to evaluate the effects of mesquite (Prosopis juliflora [Sw.] DC.) extract as phytogenic additive for sheep finished on pasture in the Brazilian Northeast semiarid region. Twenty-four intact lambs (Santa Ines × Dorper F1 crossbred) were used, with an initial body weight of 23.00 ± 1.83 kg. The experiment was carried out in a complete randomized design with four treatments and six replicates. Treatments consisted of four diets: Pasture and no supplementation; grazing pasture and phytogenic additive; pasture, supplementation with Tifton 85 hay, and concentrate; and pasture, phytogenic additive, and supplementation with Tifton 85 hay and concentrate. Prior to supplementation, animals received the phytogenic additive according to treatment. There were nonsignificant differences for nutrient intake and behavior patterns (P > 0.05). However, additive intake derived from mesquite provided an increase (P < 0.05) in digestibility (14.40% total digestible nutrients), N balance (27.12% retained N:ingested N) and performance (8.82% final body weight, 21.81% total weight gain, and 30.81% average daily gain) compared to animals consuming only pasture in rainy period. Thus, the use of mesquite extract as phytogenic additive is recommended for sheep finished on pasture in the Brazilian semiarid region.

Resumen Antecedentes: La preeclampsia es un trastorno multiorgánico asociado con la morbi-mortalidad materna y perinatal. En el Perú, su incidencia es del 10% y causa el 22% de las muertes maternas. Se encontró una asociación entre la preeclampsia y ciertos polimorfismos. Objetivo: Determinar asociación entre los polimorfismos genéticos del factor de crecimiento endotelial vascular (VEGF) +936 C/T y +405 G/C, interleucina-6 (IL-6) -174G/C, IL-1β -511 C/T, Apo A-1 -75 G/A, Apo B-100 2488 C/T (Xbal), y preeclampsia en gestantes peruanas. Métodos: Se incluyeron gestantes preeclámpticas y sanas (controles). Las muestras de sangre fueron procesadas para extracción del ADN, y el análisis se realizó con la técnica PCR-RFLP con protocolos específicos para cada gen y confirmación con secuenciamiento Sanger. Se compararon las frecuencias alélicas y genotípicas en los casos (preeclampsia) y los controles. Resultados: No se halló asociación entre los polimorfismos VEGF+936-C/T y VEGF+405 y la preeclampsia. Las frecuencias de los genotipos GG y el alelo G del polimorfismo -174-G/C en el gen IL6 en preeclámpticas y controles, mostraron diferencias significativas, con frecuencias más altas en los casos. Para el polimorfismo -511-C/T del gen IL-1β, no se encontraron diferencias significativas en las frecuencias de genotipos TT comparados con CT+CC. Los genotipos y alelos de las variantes Apo-A1-75-G/A y Apo-B100 Xbal no mostraron diferencias significativas entre los grupos Conclusión: No se encontró asociación entre los marcadores genéticos estudiados y la preeclampsia. Sin embargo, el polimorfismo -174-G/C en el gen IL6 mostró diferencias significativas principalmente en el genotipo GG y el alelo G.

Abstract Background: Preeclampsia is a multiorgan disorder associated with maternal and perinatal morbi-mortality. In Peru, incidence is 10% and accounts for 22% of maternal deaths. Genome and genetic epidemiological studies have found an association between preeclampsia and genetic polymorphisms. Objective: To determine the association of the vascular endothelial growth factor (VEGF) +936 C/T and +405 G/C, interleukine-6 (IL-6) -174 G/C, IL-1β-511 C/T, Apo A-1-75 G/A, Apo B-100 2488 C/T (Xbal) polymorphisms with preeclampsia in pregnant Peruvian women. Methods: Were included preeclamptic and healthy (control) pregnant women. Maternal blood samples were subjected to DNA extraction, and molecular genetic analysis was conducted using the PCR-RFLP technique and following a specific protocol for each gene. Allele and genotypic frequencies in the cases and controls were compared. Results: No association was found between the VEGF+936C/T and VEGF+405 polymorphisms and preeclampsia. The frequencies of the GG genotypes and the G allele of the -174 G/C polymorphism in the IL6 gene in preeclamptic and controls showed significant differences, with higher frequencies in cases. For the -511 C/T polymorphism of the IL-1β gene, no significant differences were found in the frequencies of TT genotypes compared with CT+CC. The genotypes and alleles of the Apo-A1-75 G/A and Apo-B100 Xbal variants showed no significant differences between cases and controls. Conclusion: No association was found between the studied genetic markers and preeclampsia. However, in the -174G/C polymorphism of the IL-6 gene, significant differences were found mainly in the GG genotype and G allele.

Abstract Forest ecosystems are important in the contribution of goods and services to society; however, they may be affected by water erosion, which represents a serious problem in Mexico. Therefore, the objective of this work was to determine the factors that explain this type of degradation in the temperate forest. The factors that influence water erosion were selected through literature review, nationally and internationally, with criteria for use in management and monitoring programs. To assess erosion loss, the measurement of pedestals was used. Statistically, Pearson's correlation and Principal Component Analysis (PCA) were used. The results obtained revealed that for Pearson, the apparent density (r = 0.64), slope (r = 0.59) and the percentage of rocks on the soil surface (r = 0.57), showed a positive correlation with water erosion, so by increasing their values, the presence of pedestals increases. Negative correlation was determined with depth (r = -0.48) and percentage of soil organic matter (r = -0.45). At higher magnitudes of those parameters, the presence of pedestals decreases as expressions of the degree of soil erosion. Through the PCA, they also directly influenced the thickness of the mulch, bare soil and soil compaction. Positive correlation with percentage of bare soil and compaction was also identified. While there was no significance with organic matter, infiltration capacity and soil depth. The indicated factors must be taken into account to facilitate future monitoring.

Resumen Los ecosistemas forestales son importantes en la aportación de bienes y servicios a la sociedad; sin embargo, pueden estar afectados por erosión hídrica, lo cual representa un problema grave en México. Por lo tanto, el objetivo de este trabajo fue determinar los factores que explican ese tipo de degradación en un bosque templado. Los factores incluidos fueron seleccionados mediante revisión de literatura, a nivel nacional e internacional, con el criterio de uso en programas de manejo y monitoreo. Para evaluar la pérdida por erosión, se utilizó la medición de pedestales. Estadísticamente, se emplearon la correlación de Pearson y el Análisis de Componentes Principales (ACP). Los resultados de la primera evidenciaron que la densidad aparente (r= 0.64), pendiente (r=0.59) y el porcentaje de rocas en la superficie del suelo (r=0.57) tienen correlación positiva con la erosión hídrica; por lo que, al incrementar sus valores, aumenta la presencia de pedestales. Se determinó una correlación negativa con la profundidad (r= -0.48) y el porcentaje de materia orgánica (r= -0.45). A mayor magnitud de estos parámetros, disminuye la presencia de pedestales como expresiones del grado de erosión de los suelos. Mediante el ACP, se obtuvo que, además, incidieron directamente, el espesor del mantillo, la presencia de suelo desnudo y la compactación. También, se identificó una correlación positiva con el porcentaje de suelo desnudo y la compactación. No hubo significancia con la materia orgánica, capacidad de infiltración y profundidad del suelo. Los factores señalados deben considerarse para facilitar los monitoreos futuros.

Summary Objective: To determine if an association hypercholesterolemia and cholesterolosis or gallbladder lithiasis does exist. Methods: AA case series study was conducted between January 2014 and December 2015 in Hospital Belén, Trujillo- Perú. Patients were those in whom a cholecystectomy had been performed (1069) and a lipid profile was available (143). Results: Age range was 17-95 years with a mean age of 50; 36 (25.2%) had cholesterolosis, male to female ratio was 1:2,6. Gallbladder lithiasis was found in 119 cases (83.2%), male to female ratio is 1:3.1 and a mean age of 48. Hypercholesterolemia (≥ 200 mg/dl) was found in 51 cases (35.7%); 29 20.3% cholesterolosis with gallbladder lithiasis and 7 (4.9%) had acalculous cholesterolosis. No association was found between hypercholesterolemia and cholesterolosis (p=0.284) nor with gallbladder lithiasis (p=0.169). Conclusions: No significant association between hypercholesterolemia and cholesterolosis or gallbladder lithiasis was found.

Resumen Objetivos: Determinar si existe asociación entre hipercolesterolemia y colesterolosis o litiasis vesicular. Material y métodos: Estudio de serie de casos comparativo, retrospectivo, realizado entre enero del 2014 y diciembre del 2015, en el Hospital Belén de Trujillo-Perú. Formaron parte del estudio todos aquellos casos productos de colecistectomía que tuvieron un perfil lipídico. Se revisaron 1069 historias clínicas en las que se encontraron 143 casos que tenían perfil lipídico. Resultados: El rango de edad varió entre 17 y 95 años con una edad promedio de 50 años. De estos, 36 casos (25,2%) tenían colesterolosis. La relación varón:mujer fue 1:2,6 y una edad promedio de 44,5 años. Tuvieron colecistolitiasis 119 casos (83,2%), con una relación varón:mujer 1:3,1 y una edad promedio de 48 años. Hubo hipercolesterolemia (≥ 200mg/dl) en 51 casos (35,7%). En 29 (20,3%) casos se observó colesterolosis con colecistolitiasis y 7 (4,9%) pacientes tuvieron colesterolosis acalculosa. No se encontró asociación entre hipercolesterolemia y colesterolosis (p=0,284), ni con litiasis vesicular (p=0,169). Conclusiones: No existe asociación estadísticamente significativa entre hipercolesterolemia con colesterolosis, ni con litiasis vesicular.